There has been an update to the following section of the SPC:
Change to section 4.4 - Special warnings and precautions for Use
Rifadin infusion may produce a reddish coloration of the urine, sweat, sputum and tears, and the patient should be forewarned of this. Soft contact lenses have been permanently stained (see section 4.8).
Please refer to SPC link below for full information on all changes.