There have been significant updates to several sections of the SPC, including the following:
Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
Studies in healthy subjects showed that there were no clinically relevant effects of prucalopride on the pharmacokinetics of warfarin, digoxin, alcohol, paroxetine or oral contraceptives.
Please refer to SPC link below for full information on all changes.