There have been significant updates to several sections of the SPC, including the following:

Change to section 4.2 - Posology and method of administration

In obese patients dosed with intravenous aciclovir based on their actual body weight, higher plasma concentrations may be obtained (see 5.2 Pharmacokinetic properties). Consideration should therefore be given to dosage reduction in obese patients and especially in those with renal impairment or the elderly.

Dose adjustments have been updated for infants and the elderly in accordance with creatinine clearance.

Please refer to SPC link below for full information on all changes.