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Lancet Series: Malignancies in pregnancy

Reference: Lancet – published 10th February 2012

Source: Lancet

Date published: 10/02/2012 17:11

Summary
by: Devika Sennik

The introduction to this Series of three papers notes that cancer in pregnancy often involves a difficult choice: whether to abort the foetus and to focus treatment on the health of the pregnant woman, or on the other hand to prioritise a healthy pregnancy at the cost of delaying cancer treatment to the mother. In addition, little quality research exists in this field to guide clinical practice. The Series aims to provide readers with new insights into the effective management of pregnant women with cancer.

 

The first Series paper highlights how cervical and ovarian cancers are the most common malignancies in pregnancy, and how tumour size/stage and nodal status are crucial in determining clinical management. The second paper discusses breast cancer in pregnancy, where a multidisciplinary focus and a cautious approach to radiotherapy are needed. The third and final paper highlights haematological cancers in pregnancy and notes that although rare, these cancers are challenging to manage, with therapy usually reserved for late stages of pregnancy.

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