The European Heart Journal has featured a review discussing the potential safety and efficacy of mineralocorticoid receptor antagonists in acute heart failure syndromes.

The following topics are covered:

• Acute heart failure syndrome pathophysiology

• Acute heart failure syndrome therapy

• Acute heart failure syndrome clinical profiles

• Mineralocorticoid receptor antagonists: types and molecular mechanisms (spironolactone and eplerenone)

• Mineralocorticoid receptor antagonists as diuretics