The National Prescribing Centre (NPC) has featured a ‘blog’ discussing the findings and implications of a meta-analysis of randomised controlled trials (RCTs) comparing the efficacy of inhaled corticosteroids (ICSs) versus montelukast alone and added to an ICS in schoolchildren and adolescents with mild-moderate persistent asthma. 

The meta-analysis (Arch Dis Child 2010;95:365-370) found that ICSs are significantly more effective than montelukast for preventing severe asthma exacerbations requiring systemic corticosteroids in schoolchildren and adolescents with mild-moderate asthma.  The authors of the blog say that these findings support the BTS/SIGN asthma guideline for the management of asthma; health professionals should continue to follow this guideline.  Please see the link below for further details of the research.