This review addresses the diagnostic and management dilemmas of suspected gastro-oesophageal reflux disease in preterm infants on the neonatal unit. The authors summarise the best available evidence and use this pragmatically to devise a structured, clinical management strategy to assist diagnosis and avoid over treatment.
The following management options are covered:
• Positioning and feed regime alteration
• Feed thickeners
• Pharmacological agents: erythromycin, H2 antagonists, proton pump inhibitors, domperidone