The ideal prokinetic dose of erythromycin is yet to be established but is less than the maximal antibacterial dose of erythromycin.

There is not a standard regimen for erythromycin when used as a prokinetic agent.
With intravenous erythromycin, satisfactory outcomes have been achieved with doses of 300mg daily in divided doses, with 250mg four times a day, and with single doses of 70mg and 200mg.

Oral erythromycin at prokinetic doses of 50 – 250mg four times daily have be used effectively.