Do statins cause alopecia?

Original article by: Alexandra Denby

Publisher: London Medicines Information Service

Keywords: simvastatin, atorvastatin, rosuvastatin, pravastatin, fluvastatin, alopecia

Date published: 22/03/2012 09:00

Review date: 31/03/2014 09:00

Summary
by: Alexandra Denby
  • As hair loss is a generally accepted male characteristic, drug-induced alopecia may be mistaken as part of a natural process and therefore under reported.
  • There have been reports of alopecia associated with the use of all UK licensed statins but there is insufficient data to confidently attribute hair loss to statin use.
  • Case studies suggest an association but as yet there is insufficient information to suggest a mechanism, make comparisons of the individual incidence of alopecia between the various statins or propose a class effect.
  • The greatest number of reports of alopecia is for simvastatin but this may be related to e.g. market share, length of time on market.
About this library entry
NeLM area:  Evidence > Medicines Q & A

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