This guideline from the Scottish Intercollegiate Guideline Network (SIGN) focuses on providing recommendations for the management of atopic eczema in children and adults in primary care, based on current evidence for best practice. It includes advice on topical treatments (including emollients, corticosteroids, calcineurin inhibitors and dressings), anti-infective treatments (such as antibiotics and antiseptics), antihistamines, complementary therapies and the roles of diet and environmental factors. It excludes treatments that are usually carried out in secondary care, such as phototherapy and systemic immunosuppressant drugs.