This Topic Review covers the management of adults with hyperthyroidism. The target audience is healthcare professionals working within the NHS in England, and providing first contact or primary health care. The following management issues are discussed: - How should I manage someone with overt hyperthyroidism? - How should I manage suspected subclinical hyperthyroidism? - How do I manage someone with suspected Graves' opthalmopathy? - How should I manage hyperthyroidism in a pregnant or postpartum woman? - How should I manage amiodarone- or lithium-induced hyperthyroidism? - How do I manage someone with subacute (de Quervain's) thyroiditis? - What monitoring is required for someone on hyperthyroidism treatment? - What treatments are available for hyperthyroidism treatment? - What treatments are available for hyperthyroidism in secondary care? Medicines discussed include the thionamides (carbimazole, propylthiouracil) and beta-blockers.