This Topic Minibite from the Clinical Knowledge Service (CKS) covers the management of seasonal influenza and post-exposure prophylaxis of seasonal influenza. It is based on two technology appraisals published by the National Institute for Health and Clinical Excellence (NICE):

• Guidance number 158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza, and
• Guidance (number 168): Amantadine, oseltamivir and zanamivir for the treatment of influenza