In this article in the Drug and Therapeutics Bulletin (DTB), the authors provide an update on treatments for headlice with a focus on isopropyl myristate 50% in cyclomethicone solution (Full Marks Solution), a new treatment option with a physical mode of action that uses a 10-minute contact time. They note that as the product has a physical rather than a chemical mode of action, the lice are less likely to develop resistance to it than to conventional neurotoxic insecticides. Published studies of the treatment have suggested a cure rate of up to 82%.

In terms of comparisons with other products, Full Marks solution has been compared with permethrin 1% (Lyclear crème rinse),  selected on the grounds that it is the only other product in the UK with a 10-minute contact time. However, this product has not been recommended for several years because the contact time is insufficient to kill louse eggs. Full Marks solution has also been compared with a combination product containing pyrethrin 0.33% plus piperonyl butoxide 4%, but this product is not available in the UK. For these reasons, the authors conclude that until data are available  directly comparing Full Marks solution with other commonly used insecticides in the UK, with dimeticone or with wet combing methods such as bug busting. it cannot be recommended in preference to established treatments for patients with head lice.